三、主要科研工作与成绩 科研团队：现有教授、特聘教授2名，讲师1名，博士后2名，团队50%成员拥有海外留学经历；在读博士4名，硕士生8名。 科研项目： [1] 国家自然科学基金面上项目（31371776），“nox1 基因对单增李斯特菌菌膜形成及毒力调控机制”，2014.01-2017.12。 [2] 上海市科委（13430502400），“基于“蛋白宏阵列筛选技术”的食源性致病菌快速检测技术研究”，2013.01-2016.09。 [3] 上海市科委（15395810900），“供沪生鲜食品食源性致病菌分型数据库及风险溯源平台构建及示范”，2015.06-2017.05 [4] 横向课题（3A15308006），“乳制品生产体系致病菌快速检测”，2015.1-2017.12。 近年专利：近三年共申请专利39项目，其中已授权发明专利9项，实用新型专利10项。 对外合作：德国University Freiburg医学院、美国Case Western Reserve University生物系、University of California at Los Angeles医学院。. 近年论文： [1] Wu M1, Li H, Jiang Y, Song C, Guo H, Wu S, Liu C, Li J, Zeng H, Zhai X, Zhang W, Fan E, Liu Q*. Simultaneous quantification of Escherichia coli O157:H7 and Shigella boydii using a visual-antibody-macroarray. Analyst(2015);140(19):6595-601. [2] Qiu S, Song C, Zhao S, Li J, Zeng H, Wu S, Guo H, Li H, Liu C, Liu Q*. A new spot quality control for protein macroarray based on immunological detection. Talanta(2015);138:176-82. [3] Chunmei Song, Cheng Liu, Shuyan Wu, Haolin Li, Huiqin Guo, Biao Yang,Shi Qiu, Jianwu Li, Lan Liu, Haijuan Zeng, Xuzhao Zhai, Qing Liu *, Development of a lateral flow colloidal gold immunoassay strip for the simultaneous detection of Shigella boydii and Escherichia coli O157:H7 in bread, milk and jelly samples. Food Control 59 (2016) 345-351. [4] Liangbin Xiong,Liping Gao, Qing Liu,* Junfang Xia, Xiaoyan Han and Yali Liu.A simple, rapid and visual antibody array for the simultaneous detection of multiple plant pathogens. Anal. Methods(2013) 5, 2413. [5]Dong J, Chen P, Liu Q, Wang R, Xiao W, Zhang Y.Reverse effects of DPI administration combined with glutamine supplementation on function of rat neutrophils induced by overtraining. Int J Sport Nutr Exerc Metab(2013);23(2):137-49. [6] Mu P, Liu Q, Zheng R. Biphasic regulation of H2O2 on angiogenesis implicated NADPH oxidase,Cell Biol Int(2010);34(10):1013-20. [7] Liu Q, He X, Liu Y, Du B, Wang X, Zhang W, Jia P, Dong J, Ma J, Wang X, Li S, Zhang H.NADPH oxidase-mediated generation of reactive oxygen species: A new mechanism for X-ray-induced HeLa cell death. Biochem Biophys Res Commun(2008) 19;377(3):775-9. [8]Liu JJ, Liu Q, Wei HL, Yi J, Zhao HS, Gao LP. Inhibition of thioredoxin reductase by auranofin induces apoptosis in adriamycin-resistant human K562 chronic myeloid leukemia cells. Pharmazie(2011) 66(6):440-4. [9]Gao C, Cheng X, Lam M, Liu Y, Liu Q, Chang KS, Kao HY. Signal-dependent regulation of transcription by histone deacetylase 7 involves recruitment to promyelocytic leukemia protein nuclear bodies. Mol Biol Cell (2008);19(7):3020-7. [10] Reineke EL1, Lam M, Liu Q, Liu Y, Stanya KJ, Chang KS, Means AR, Kao HY. Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells. Mol Cell Biol(2008) ;28(3):997-1006.
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